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M. Sc. Maria Logotheti
Institute of Biochemistry
University of Greifswald
Felix-Hausdorff-Str. 4
17487 Greifswald
Email: Maria.Logotheti@uni-greifswald. de
Research Experience
2020-today PhD candidate (Photobiocatalysis), Ernst-Moritz-Arndt-University of Greifswald
2017-2019 Research employee (Functional and structural characterization of enzymes), Max-Planck-Institute for Developmental Biology Tübingen
2013-2014 Analytical chemist (internship; quality control of pharmaceutical products and food supplements), National Organization for Medicines, Biological and Toxicological Control Section, Athens
Education
2017 M.Sc. in Biochemistry, Eberhard-Karls-University of Tübingen
2014 B.Sc. in Chemistry, National and Kapodistrian University of Athens
2009 High School Apolytirion
Awards
2014-2016 DAAD scholarship for (postgraduate) studies in Germany
Project
The PhD project aims at the integration of biocatalysis and photocatalysis for the development of novel photochemo-enzymatic conversions of simple substrates into synthetically useful building blocks or chemical products of interest. The combination of photo-catalysis and enzymatic catalysis in one-pot is quite challenging due to incompatibility problems between them. Herein, it is aspired to address the associated obstacles and thus, harness the benefit and complementarity of the two catalysis disciplines to develop a new process for the production of amines.
Further ideas on alternative photo-enzymatic combinations and/or interesting substrates are welcome.
Within this scope, Maria started a collaboration with the research group of Professor Malte Brasholz with the aim to exchange ideas and technical support utilising the complementary expertises of the two groups on photo- and bio-catalysis. Furthermore, she collaborates with Paul Hünemörder and Dr. Esteban Meija. Within this collaboration it is aspired to transfer a metal-photoactivated C-H fuctionalization reaction into a suitable protein host to achieve stereoselectivity.
Motivation
"The focus on interdisciplinary science by bringing different fields of catalysis together, with the aim to design more sustainable alternatives to existing synthetic procedures"