Matthias Höhne - Universität Greifswald
Phone: +49 (0)3834/420-4417
Visit website: https://biochemie.uni-greifswald.de/forschung/forschung-in-den-arbeitskreisen/ordner-aks-lehrstuehle/proteinbiochemie/
Within the ERC-starting grant project (starting 2018), we will create proteins that use light to catalyse regio- and stereoselective reactions. During evolution, new types of catalytic activities have been unlocked by utilizing additional cofactors. We will follow this thread of development and combine the strengths of bio- and photocatalysis: organo-photocatalysts will be placed as artificial cofactors into proteins to provide the protein with novel catalytic reactivities, and the proteins will be evolved to assist the catalytic reaction and to render it regio- and stereoselective.